Platelet Rich Plasma (PRP)

PRP Clinic in bangalore

What is PRP?

PRP is a concentrated blood product that contains a high percentage of platelets (biomolecules with natural healing and regenerative properties). To understand more, let’s take a step back and look at blood as a whole. In general, whole blood is composed of 4 main components:

    • Plasma: the liquid component of blood that consists mostly of water, dissolved salts and proteins. It constitutes more than half of blood volume and provides the medium for all other components in the blood to be transported throughout the body.
    • Platelets: Also known as thrombocytes, platelets are cell-like particles that help in the clotting process and release other substances and growth factors.
    • Red Blood Cells: Also called erythrocytes, red blood cells carry oxygen is involved in the exchange of Oxygen and Carbon Dioxide, brining oxygen to tissue, and removing carbon dioxide from the body.
    • White Blood Cells: Also known as leukocytes) are white blood cells are primarily responsible for the body’s immune system.
How is PRP prepared ?

PRP is most often used from the person’s blood undergoing the PRP therapy but can be made from another individual’s blood.

  • Step 1: The PRP process starts with a healthcare professional drawing a sample of blood similar to how they would normally collect tubes of blood.
  • Step 2: The blood is centrifuged (put in a machine that spins very quickly causing the different components of blood to separate) for about 15 minutes.
  • Step 3: A lab technician collects the plasma (now rich in platelets and devoid of cellular components) in preparation for its injection.
PRP for Egg Quantity & Quality

PRP may be used to encourage an improvement in egg quality, ovarian rejuvenation, and response to stimulation medications.

  • There are two ways/procedures in which PRP may be used to improve oocyte quality and quantity:
  • Intraovarian PRP
  • This procedure involves injecting 1-3 mls of PRP directly into the ovaries. This procedure is done under monitored anesthesia care by a physician. During the procedure a needle with the PRP is guided via ultrasound through the vaginal wall and into the ovaries where the PRP will then be deposited.
PRP for Uterine Lining Growth & Endometrial Receptivity (PRP Intrauterine Wash)

PRP may be used to improve the endometrial receptivity of the uterine lining prior to an embryo transfer. This is typically done 48 hours prior to the anticipated embryo transfer. During the procedure, approximately 3-5 mls are infused in the uterus using an IUI catheter. The patient will rests for 10 mins and is subsequently discharged for normal daily activity. This procedure may be performed by an RN, NP, PA, OBGYN, or reproductive endocrinologist.

If the infusions are intended for lining development (usually for someone with a history of failing to develop an adequate uterine lining) the uterine wash may be performed in a series of procedures. The first PRP infusion would be done at the initial lining check and then repeated 72 hours later if the lining remains inadequate.

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